Unfortunately it is no longer available!
The Good News - 6 OXO is the closest Non-Hormonal Anabolic available to replace 1-AD
6 OXO After years of research into natural estrogen blockers finally a compound that really truly works, in males, to both reduce estrogen and increase testosterone. Its called 6-OXO™.
1 AD by Ergopharm is undoubtly the strongest pro hormone ever produced, and now this second batch is even more amazing. This batch utilizes the "diol" version of the molecule, which unlike the previous 1 AD version will not irritate the stomach . 1 AD produces the same incredible muscle and strength gains without hassle because it is no longer necessary to take with food.
It's A Natural Hormone Made in the Body
One of the remarkable things about 1 AD is that in addition to its impressive
pharmacological activity, it is also a natural androgen produced by the human
body. This means that 1 AD is not foreign to your body, and that it can sold
legally as a nutritional supplement. Additionally, 1AD’s high rate of active conversion
after oral administration is not just a “theory” of ErgoPharm’s. It has
been demonstrated and published in a reputable peer reviewed journal.
*These statements about 1 AD have not been evaluated by the Food and Drug Administration. 1 AD is not intended to diagnose, treat, cure, or prevent any disease.
Before we introduce exactly what 1 AD is, we want to mention one quick thing. In this industry it is often hard to find straight answers to exactly what something is, and how something works. Most often, the case is that the company is evasive with the facts because there really is no existing science that validates the claims they are making. Either that or they simply do not understand the science themselves. Occasionally a company does have science to back up their products, but they decide that the consumer is too simple minded to appreciate the facts.
ErgoPharm is different. We produce products that are backed up by hard scientific fact, and we take great pride in laying everything on the table.
The Power of 1-Testosterone
You probably are familiar with the “Andro” pro hormones, and the “Norandro” pro hormones. The former convert to testosterone and the latter to 19-nortestosterone. 1 AD, however, does not fit into either of those categories. That is because 1AD converts to a relatively unheard of hormone called 1-testosterone. 1-testosterone is what is known as a “double bond isomer” of testosterone.
Although chemically the only difference between testosterone and 1-testosterone is the position of the double bond, pharmacologically the two products are quite different. According to research done by the pharmaceutical giant G.D. Searle and published in the 1960s, 1-testosterone is over 7 times as myotrophic (anabolic) as testosterone(1). That makes 1-testosterone a phenomenally potent compound, surpassing even most synthetic anabolic steroids.
1-testosterone differs from testosterone in another way as well. Being a 5alpha-reduced androgen (a DHT derivative) it simply cannot aromatize to estrogens. The same goes for 1 AD itself — no estrogen transformation can occur. This makes 1 AD unique compared to other pro hormones — all of which can either aromatize directly, convert to a product that aromatizes, or both. So what does this mean in the real world? It means that your chances of getting gynecomastia (bitch tits) from 1AD is essentially zero, and that water retention side effects are vastly reduced compared to other pro hormones.
The Only Truly “Orally Active” Pro hormone
Natural androgenic steroids are normally not very active orally. Large amounts have to be taken orally to see biological effects. This is because the first pass through the liver causes a massive deactivation of the compounds, primarily through the oxidation of the 17beta-hydroxyl to a 17-keto group. Chemists long ago found that by adding an alkyl (methyl or ethyl) chemical group to the alpha position of the 17 carbon, this oxidation can be prevented. However, this alkyl derivatization also greatly increases the liver toxicity. Therefore the usage of such synthetically altered compounds (methyltestosterone, oxymetholone, stanozolol) are not without substantial risk.
Luckily, there are other ways to render a steroid orally active, and do so without making the compound toxic to the liver. Certain structural modifications can alter the metabolism of steroids making them resistant to liver breakdown. One of these modifications is unsaturation (presence of a double bond) in the 1-position. One steroid that has this structural modification and is orally active is the anabolic steroid Methenolone, also known as Primobolan. As you may have noticed, this double bond position that makes Primobolan orally active is the same one found in 1-AD, which, by the way, is also orally active. Steroids with this particular double bond characteristic are known as 1-dehydroandrostanes.
During the 60’s and 70’s some papers were published describing the phenomenon of oral activity seen with 1-dehydroandrostanes, including 1-testosterone and 1 AD. What was discovered was that these compounds resist metabolic deactivation by profoundly shifting what is known as the “17-keto redox potential” towards the formation of active 17beta-hydroxyl steroids(2,3). What does this mean? It means that when you take 1 AD, the liver serves primarily to activate the compound, rather than break it down and excrete it as it does with other pro hormones and testosterone. It means that 1-AD is “orally active,” yet it does not impart the liver toxicity that 17alpha-alkylation does.
A Natural Hormone Made in the Body
One of the beautiful things about 1-AD is that in addition to its impressive pharmacological activity, it is also a natural androgen made in the human body(4) . This means that it is not foreign to your body, and that it can legally and openly be sold as a nutritional supplement. Furthermore, 1-AD’s high rate of active conversion after oral administration is not just a “theory” of ErgoPharm’s – it has been demonstrated and published in a highly reputable peer reviewed journal.
Let’s put it all together and see what 1AD has to offer:
There can be no argument that this is the
ultimate pro hormone. Believe us, there simply are no natural compounds out there
that can come close to what 1AD does, so don’t even bother looking.
6 OXO is the closest Non-Hormonal Anabolic available to replace 1-AD
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